DigiONE-I3

DIGItal Infrastructure for ONcology in Europe

The DigiONE I3 (Interregional Innovation Investments) proposal creates a federated, privacy appropriate, high quality, digital research network that links routine clinical data with routine molecular data information from 15 large cancer centres in 9 countries, with 10 private partners in 18 S3 regions. The underlying digital infrastructure provides a minimal description of every patient’s cancer diagnosis, biomarkers, treatment and outcomes in near real time & internationally standardised. It is built on open standards and through open innovation with multiple private sector vendors. 

Precision oncology researchers access federated, privacy-managed fee-for-service, reliable protocolised insights with which to study modern cancer treatments and diagnostics in real world data, or for health systems analysis to improve cancer care. The economic model will reflect differences in ability to pay and IP requirements: at-cost, open-source access for academics with peer-reviewed non-commercial funding, and fair-market-value pricing for larger companies developing patented commercial products. 

DigiONE I3 will serve to develop two new value chains that promote economic growth and increase jobs: (1) in providing digital research services to the global pharma/life science industry including trials and care quality analytics, and (2) by catalysing a vibrant and competitive European market in digital services to hospitals that supports Europe’s digital modernisation agenda. I3 income will bridge the gap from technology proof of concept to a commercially relevant network with the scale to recruit to rare subgroups in precision oncology research.

This project secured funding from The Interregional Innovation Investments Instrument, a part of the European Regional and Development Fund (ERDF), through a grant awarded in 2023.

The Project Lead

The Team

Partners

  • Digital Institute for Cancer Outcomes Research (DIGICORE), Brussels, Belgium
  • Grand Hôpital de Charleroi, Charleroi, Belgium
  • Masarykuv Onkologicky Ustav, Brno, Czechia
  • Sihtasutus Tartu Ulikooli Kliinikum, Tartu, Estonia
  • Charité - Universitätsmedizin Berlin, Berlin, Germany
  • Universitätsmedizin Greifswald Körperschaft des Öffentlichen Rechts, Greifswald, Germany
  • Technische Universität Dresden, Dresden, Germany
  • The Provost, Fellows, Foundation Scholars & the other members of Board, of the College of the Holy & Undivided Trinity of Queen Elizabeth near Dublin, Dublin, Ireland
  • Istituti Fisioterapici Ospitalieri, Rome, Italy 
  • Ospedale San Rafaele SRL, Milan, Italy 
  • Viesoji Istaiga Vilniaus Universiteto Ligonine Santaros Klinikos, Vilnius, Lithuania
  • Maastricht University, Maastricht, The Netherlands
  • Stichting Maastricht Radiation Oncology (Maastro), Maastricht, The Netherlands
  • Academisch Ziekenhuis Groningen, Groningen, The Netherlands 
  • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie -Panstwowy Instytut Badawczy, Warsaw, Poland
  • EuroScan International Network EV, Cologne, Germany 
  • EdenHealth, Brussels, Belgium 
  • IQVIA Cancer Research, Zaventem, Belgium 
  • ONCODNA, Charleroi, Belgium
  • KAIROS GMBH, Bochum, Germany
  • IQVIA SOLUTIONS BV, Amsterdam, The Netherlands
  • MAASTRO INNOVATIONS BV, Maastricht, The Netherlands 
  • MEDICAL DATA WORKS BV, Maastricht, The Netherlands 
  • Clininote Spolka z Ograniczonaodpowiedzialnoscia, Lublin, Poland
  • CompuGroup Medical Polska Spolka Ograniczona Odpowiedzialnoscia, Lublin, Poland
  • Instytut Matki i Dziecka, Warsaw, Poland