STRATA-FIT

Strategies for difficult-to-treat disease

The STRATA-FIT consortium sets out to develop and validate computational models to identify and stratify Difficult-to-treat rheumatoid arthritis (D2T RA) patients into clinically relevant phenotypes using real world clinical data.

D2T RA is a subgroup of rheumatoid arthritis patients and it is an area of huge unmet medical need with major socio-economic consequences for patients and society. Contributing factors have been identified including co-morbidities, drug-related, biological and behavioral factors.

However, identifying these patients with specific underlying and overlapping problems, or patients at risk, is a big challenge in practice. Currently, treatment decisions are random and not sufficiently patient tailored nor data-driven.

This project was awarded funding by Horizon Europe in 2022.

The Project Lead

Partners

  • EULAR, Zürich, Switzerland
  • Instituto de Medicina Molecular, Joao Lobo Antunes
  • Karolinska Institutet, Stockholm, Sweden
  • Karolinska University Hospital, Stockholm, Sweden
  • LMU, München, Germany
  • LMU Klinikum, München, Germany
  • Medizinische Universität Wien, Wien, Austria
  • Medical Data Works, Maastricht, The Netherlands 
  • Semmelweis University, Budapest, Hungary
  • UMC Utrecht, Utrecht, The Netherlands